Urate Transporters in the Kidney: What Clinicians Need to Know
Sungjin Chung, Gheun‐Ho Kim
Abstract
inhibit urate secretion from the gut and kidney and may cause gout. In summary, the net result of urate transport in the proximal tubule is determined by the dominance of transporters between reabsorption (URAT1, OAT4, and GLUT9) and secretion (ABCG2, NPT1, NPT4, OAT1, and OAT3).
Topics & Concepts
TransporterKidneyMedicineUric acidNeed to knowIntensive care medicineChemistryComputational biologyInternal medicineBiochemistryBiologyComputer scienceGeneComputer securityGout, Hyperuricemia, Uric AcidUrological Disorders and TreatmentsGastroesophageal reflux and treatments