SARS-CoV-2 reinfection caused by the P.1 lineage in Araraquara city, Sao Paulo State, Brazil
Camila Malta Romano, Alvina Clara Félix, Anderson Vicente de Paula, Jaqueline Góes de Jesus, Pâmela dos Santos Andrade, Darlan da Silva Cândido, Franciane Mendes de Oliveira, Andreia C. Ribeiro, Francini C. da Silva, Marta Inemami, Ângela Costa, Cibele O. D. Leal, Walter Manso Figueiredo, Claudio Sergio Pannuti, William Marciel de Souza, Nuno R. Faria, Éster Cerdeira Sabino
Abstract
Reinfection by the severe acute respiratory syndrome coronavirus type 2 (SARS-COV-2) has been reported in many countries, suggesting that the virus may continue to circulate among humans despite the possibility of local herd immunity due to massive previous infections. The emergence of variants of concern (VOC) that are more transmissible than the previous circulating ones has raised particular concerns on the vaccines effectiveness and reinfection rates. The P.1 lineage was first identified in December 2020 in Manaus city and is now globally spread. We report the first case of reinfection of SARS-CoV-2 caused by the P.1 variant outside of Manaus. The potential of these new variants to escape naturally and vaccine- induced immunity highlights the need for a global vigilance.