Au(I)/(<i>R</i>)-BINOL–Ti(IV) Concerted Catalyzed Asymmetric Cascade Cycloaddition Reaction of Arylalkynols
Hongkai Wang, Tianlong Zeng, Weixing Chang, Lingyan Liu, Jing Li
Abstract
. Meanwhile, three new σ bonds and three new stereogenic centers were formed in a one-pot process.
Topics & Concepts
StereocenterBimetallic stripCycloadditionChemistryCatalysisYield (engineering)Bicyclic moleculeCascadeCascade reactionCombinatorial chemistryMedicinal chemistryStereochemistryEnantioselective synthesisOrganic chemistryMaterials scienceMetallurgyChromatographyCatalytic Alkyne ReactionsSynthesis and Catalytic ReactionsAsymmetric Synthesis and Catalysis