Self-assembly of peptides in living cells for disease theranostics
Xiaowei Mo, Zeyu Zhang, Jinyan Song, Yushi Wang, Zhilin Yu
Abstract
tunable assembly to precisely create biomedical materials. In this review, we summarize the progress in the self-assembly of peptides in living cells for disease diagnosis and therapy. After a brief introduction to the basic design principles of peptide assembly systems in living cells, the applications of peptide assemblies for bioimaging and disease treatment are highlighted. The challenges in the field of peptide self-assembly in living cells and the prospects for novel peptide assembly systems towards next-generation biomaterials are also discussed, which will hopefully help elucidate the great potential of peptide assembly in living cells for future healthcare applications.
Topics & Concepts
Biocompatible materialNanotechnologyChemistryBiophysicsMaterials scienceMedicineBiologyBiomedical engineeringSupramolecular Self-Assembly in MaterialsAdvanced biosensing and bioanalysis techniquesNanoplatforms for cancer theranostics