Luteolin inhibits inflammation and M1 macrophage polarization in the treatment of Pseudomonas aeruginosa-induced acute pneumonia through suppressing EGFR/PI3K/AKT/NF-κB and EGFR/ERK/AP-1 signaling pathways
GU Meng-di, Zheng Pang
Topics & Concepts
Protein kinase BMAPK/ERK pathwayPI3K/AKT/mTOR pathwayLuteolinMacrophage polarizationInflammationSignal transductionPseudomonas aeruginosaCancer researchChemistryNF-κBMacrophageMedicineBiologyFlavonoidImmunologyBacteriaBiochemistryIn vitroGeneticsAntioxidantImmune Response and InflammationImmune cells in cancerImmune responses and vaccinations