Enzyme activity engineering based on sequence co-evolution analysis
Donghyo Kim, Myung Hyun Noh, Minhyuk Park, Inhae Kim, Hyunsoo Ahn, Dae-yeol Ye, Gyoo Yeol Jung, Sanguk Kim
Topics & Concepts
Directed evolutionEnzymeDirected Molecular EvolutionBiochemistryBiologyProtein engineeringActive siteEnzyme assaySequence spaceComputational biologyDehydrogenaseGeneticsGeneBanach spaceMathematicsPure mathematicsMutantMicrobial Metabolic Engineering and BioproductionCRISPR and Genetic EngineeringRNA and protein synthesis mechanisms