Psoralen and isopsoralen from Psoraleae Fructus aroused hepatotoxicity via induction of aryl hydrocarbon receptor-mediated CYP1A2 expression
Cai Zhang, Jin‐Quan Zhao, Jia‐Xing Sun, Hui‐Jun Li
Topics & Concepts
CYP1A2Aryl hydrocarbon receptorChemistryPsoralenPharmacologyIn vivoBiochemistryIn vitroBiologyTranscription factorMicrosomeBiotechnologyDNAGeneBioactive natural compoundsPharmacogenetics and Drug MetabolismPlant chemical constituents analysis