Activity-dependent regulome of human GABAergic neurons reveals new patterns of gene regulation and neurological disease heritability
Gabriella L. Boulting, Ershela Durresi, Bulent Ataman, Maxwell A. Sherman, Kevin Mei, David A. Harmin, Ava C. Carter, Daniel R. Hochbaum, Adam Granger, J Engreitz, Siniša Hrvatin, Michael R. Blanchard, Marty G. Yang, Eric C. Griffith, Michael E. Greenberg
Topics & Concepts
BiologyEnhancerNeuroscienceGABAergicEpigeneticsInduced pluripotent stem cellForebrainPromoterPremovement neuronal activityGene expressionGeneGeneticsEmbryonic stem cellCentral nervous systemInhibitory postsynaptic potentialAutism Spectrum Disorder ResearchCongenital heart defects researchCRISPR and Genetic Engineering