Design, synthesis, and biological evaluation of benzo[d]oxazole-2-thio and oxazolo[4,5-b]pyridine-2-thio derivatives: molecular docking, POM analysis, in silico pharmacokinetics, and pharmacophore insights for antitumor, GPCR, and kinase targets
Pankaj B. Gour, Sumeer Ahmed, Ramalingam Gajendhiran, A. KalilurRahiman, Mukhtar Ahmed, Khairi Mustafa Fahelelbom, Taïbi Ben Hadda, Ajmal R. Bhat, Tulshiram L. Dadmal
Topics & Concepts
ChemistryPharmacophoreOxazoleThio-In silicoDocking (animal)PyridineCombinatorial chemistryPharmacokineticsStereochemistryComputational biologyPharmacologyBiochemistryOrganic chemistryGeneBiologyNursingMedicineSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsQuinazolinone synthesis and applications