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The Ingenuity of Bacterial Genomes

Paul C. Kirchberger, Marian L. Schmidt, Howard Ochman

2020Annual Review of Microbiology67 citationsDOI

Abstract

The genomes of bacteria contain fewer genes and substantially less noncoding DNA than those of eukaryotes, and as a result, they have much less raw material to invent new traits. Yet, bacteria are vastly more taxonomically diverse, numerically abundant, and globally successful in colonizing new habitats compared to eukaryotes. Although bacterial genomes are generally considered to be optimized for efficient growth and rapid adaptation, nonadaptive processes have played a major role in shaping the size, contents, and compact organization of bacterial genomes and have allowed the establishment of deleterious traits that serve as the raw materials for genetic innovation.

Topics & Concepts

GenomeBacterial genome sizeBiologyIngenuityAdaptation (eye)BacteriaEvolutionary biologyGenome sizeGeneGeneticsNeuroscienceEconomicsNeoclassical economicsGenomics and Phylogenetic StudiesBacteriophages and microbial interactionsCRISPR and Genetic Engineering
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