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The indole-hydantoin derivative exhibits anti-inflammatory activity by preventing the transactivation of NF-κB through the inhibition of NF-κB p65 phosphorylation at Ser276

Xin Lin, Kenji Tago, Nozomi Okazaki, Takanori So, Kyôko Takahashi, Tadahiko Mashino, Hiroomi Tamura, Megumi Funakoshi‐Tago

2021International Immunopharmacology20 citationsDOI

Topics & Concepts

HydantoinIndole testCXCL1ChemistryNF-κBPhosphorylationTransactivationIκBαBiochemistryStereochemistryMolecular biologyBiologySignal transductionGene expressionReceptorChemokineGeneNF-κB Signaling PathwaysImmune Response and InflammationBioactive Compounds and Antitumor Agents
The indole-hydantoin derivative exhibits anti-inflammatory activity by preventing the transactivation of NF-κB through the inhibition of NF-κB p65 phosphorylation at Ser276 | Litcius