Ponatinib: An update on its drug targets, therapeutic potential and safety

Yue Gao, Yue Ding, Xinran Tai, Chen Zhang, Dong Wang

2023Biochimica et Biophysica Acta (BBA) - Reviews on Cancer33 citationsDOI

Topics & Concepts

PonatinibMedicineTyrosine-kinase inhibitorTyrosine kinasePharmacologyDrugToxicityDrug discoveryLeukemiaBosutinibMyeloid leukemiaCancerCancer researchBioinformaticsOncologyDasatinibImatinibInternal medicineBiologyReceptorChronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia ResearchPI3K/AKT/mTOR signaling in cancer