Progressive immune dysfunction with advancing disease stage in renal cell carcinoma
David A. Braun, Kelly Street, Kelly P. Burke, David L. Cookmeyer, Thomas Denize, Christina B. Pedersen, Satyen H. Gohil, Nicholas R. Schindler, Lucas Pomerance, Laure Hirsch, Ziad Bakouny, Yue Hou, Juliet Forman, Teddy Huang, Shuqiang Li, Ang Cui, Derin B. Keskin, John A. Steinharter, Gabrielle Bouchard, Maxine Sun, Erica Pimenta, Wenxin Xu, Kathleen M. Mahoney, Bradley A. McGregor, Michelle S. Hirsch, Steven L. Chang, Kenneth J. Livak, David F. McDermott, Sachet A. Shukla, Lars Rønn Olsen, Sabina Signoretti, Arlene H. Sharpe, Rafael A. Irizarry, Toni K. Choueiri, Catherine J. Wu
Topics & Concepts
Immune systemImmunotherapyCancer researchTumor microenvironmentClear cell renal cell carcinomaCD8Renal cell carcinomaBiologyT cellMyeloidCytotoxic T cellCellImmunologyCancerMedicineInternal medicineBiochemistryGeneticsIn vitroCancer Immunotherapy and BiomarkersSingle-cell and spatial transcriptomicsImmune cells in cancer