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3.6 An Amplifier-Less CMOS Potentiostat IC Consuming 3.7nW Power all over 129.5dB Dynamic Range for Electrochemical Biosensing

Muhammad Abrar Akram, Aida Aberra, Soon-Jae Kweon, Sohmyung Ha

202413 citationsDOI

Abstract

Ultra-low-power potentiostats, which perform high-precision current measurements for electrochemical biosensing, hold paramount importance in the development of health-monitoring wearables, point-of-care (PoC), and implantable diagnostics. In this application, the power budget is gravely limited (sub-μW), and the input current signal varies from pA to μA range, which corresponds to a dynamic range (DR) of >120dB [1, 2]. These requirements become more stringent in some applications, such as single-molecule biosensors, where the desired signal currents exist within the nA range amidst the backdrop of background currents in the nA-to-μA range [1], and millimeter-sized electrochemical sensors, where the power efficiency is crucial.

Topics & Concepts

PotentiostatDynamic rangeCMOSAmplifierWide dynamic rangeBiosensorMaterials scienceElectrical engineeringOptoelectronicsElectronic engineeringComputer scienceElectrochemistryPhysicsEngineeringNanotechnologyElectrodeQuantum mechanicsNeuroscience and Neural EngineeringAnalog and Mixed-Signal Circuit DesignAdvanced Memory and Neural Computing
3.6 An Amplifier-Less CMOS Potentiostat IC Consuming 3.7nW Power all over 129.5dB Dynamic Range for Electrochemical Biosensing | Litcius