Biodegradable Polymer with Effective Near‐Infrared‐II Absorption as a Photothermal Agent for Deep Tumor Therapy
Yingjie Yu, Dongsheng Tang, Chaoyong Liu, Qi Zhang, Lin Tang, Yunfeng Lu, Haihua Xiao
Abstract
Photothermal therapy holds great promise for cancer treatment due to its effective tumor ablation and minimal invasiveness. Herein a new class of biodegradable photothermal agents with effective adsorption in both near-infrared-I (NIR-I) and NIR-II windows is reported for deep tumor therapy. As demonstrated in a deep-seated ovarian cancer model, photothermal therapy using 1064 nm irradiation effectively inhibits tumor progression and prolongs survival spans. This work provides a new design of photothermal agents toward a more effective therapy of tumors.
Topics & Concepts
Photothermal therapyMaterials scienceTumor ablationCancer therapyRadiation therapyAbsorption (acoustics)Photothermal effectAblationNanotechnologyCancerMedicineInternal medicineComposite materialNanoplatforms for cancer theranosticsExtracellular vesicles in diseaseAdvanced Nanomaterials in Catalysis