Novel targeted pH-responsive drug delivery systems based on PEGMA-modified bimetallic Prussian blue analogs for breast cancer chemotherapy
Qiang Chen, Xiaoyu Huang, Geyi Zhang, Jiangnan Li, Yang Liu, Yan Xu
Abstract
evaluation of anti-BC efficacy further confirmed that the obtained PBA-DDSs exhibited excellent therapeutic efficacy with limited side-effects. Therefore, the proposed novel PBA-DDSs can be used as secure and effective drug nano-DDSs for BC chemotherapy.
Topics & Concepts
In vivoDoxorubicinDrug deliveryBiocompatibilityPrussian blueTargeted drug deliveryChemistryMaterials scienceNanomedicinePharmacologyNanotechnologyChemotherapyNanoparticleMedicineSurgeryOrganic chemistryElectrodeElectrochemistryPhysical chemistryBiotechnologyBiologyNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsGraphene and Nanomaterials Applications