Sclareol ameliorated ERCC1-mediated cisplatin resistance in A549 human lung adenocarcinoma cells and a murine xenograft tumor model by suppressing AKT-GSK3β-AP1/Snail and JNK-AP1 pathways
Chun Pan, Shih‐Yin Chen, Jie-Yu Wang, Shu‐Ping Tsao, Hui-Yu Huang, Philip Wei-Chen Chiu, Chieh‐Hsi Wu
Topics & Concepts
CisplatinERCC1Cancer researchLung cancerA549 cellPharmacologyChemistryBiologyInternal medicineMedicineChemotherapyBiochemistryDNA repairNucleotide excision repairGeneCaveolin-1 and cellular processesCancer Cells and MetastasisMicrotubule and mitosis dynamics