Targeting the p38α pathway in chronic inflammatory diseases: Could activation, not inhibition, be the appropriate therapeutic strategy?
Chew Kiat Matthew Heng, Nechama Gilad, Ilona Darlyuk‐Saadon, W.S. Fred Wong, David Engelberg
Topics & Concepts
p38 mitogen-activated protein kinasesInflammationProtein kinase AHsp27Downregulation and upregulationMAPK/ERK pathwaySignal transductionCell biologyMedicineCancer researchKinaseBiologyImmunologyHeat shock proteinBiochemistryHsp70GeneMelanoma and MAPK PathwaysComputational Drug Discovery MethodsHeat shock proteins research