Comprehensive Analysis of the PD-L1 and Immune Infiltrates of m6A RNA Methylation Regulators in Head and Neck Squamous Cell Carcinoma
Lilan Yi, Guowu Wu, Longhua Guo, Xiaofang Zou, Ping Huang
Abstract
A regulator-based signatures might serve as crucial mediators of TIME in HNSCC, representing promising therapeutic targets in improving immunotherapeutic efficacy.
Topics & Concepts
Head and neck squamous-cell carcinomaImmune systemRegulatorPI3K/AKT/mTOR pathwayCancer researchBiologyDownregulation and upregulationRNA methylationTumor microenvironmentImmunotherapyCohortMethylationOncologyInternal medicineCancerMedicineHead and neck cancerImmunologySignal transductionGeneCell biologyMethyltransferaseBiochemistryRNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation