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A robust deep learning algorithm for lung cancer detection from computed tomography images

H. Abe, Mpumelelo Nyathi, Akintunde Akangbe Okunade, W. Pilloy, Becky Kgole, Nozipho Nyakale

2025Intelligence-Based Medicine24 citationsDOIOpen Access PDF

Abstract

Detecting lung cancer at its earliest stage offers the best possibility for a cure. Chest computed tomography (CT) scans are a valuable tool for early diagnosis. However, the initial stages of lung cancer may present patterns in the images that are not easily detectable by radiologist , potentially leading to misdiagnosis. Although automated approaches using deep learning (DL) algorithms have been proposed, it depends on a substantial amount of data to achieve diagnostic accuracy comparable to that of radiologists. To alleviate this challenge, this study proposes a DL algorithm that uses an ensemble of convolutional neural networks and trained on relatively small dataset (IQ_OTH/NCCD dataset) to automate lung cancer diagnosis from patient chest CT scans. The method achieved an accuracy of 98.17 %, a sensitivity of 98.21 %, and a specificity of 98.13 % when categorizing scans as either cancerous or non-cancerous. Similarly, it achieved an accuracy of 95.43 %, a sensitivity of 93.40 %, and a specificity of 97.09 % when classifying scans as normal or containing benign or malignant pulmonary nodules . These results demonstrate superior performance compared to previously proposed models, highlighting the effectiveness of DL algorithms for early lung cancer diagnosis and providing a valuable tool to assist radiologists in their assesments.

Topics & Concepts

Computed tomographyLung cancerArtificial intelligenceDeep learningTomographyComputer scienceLung cancer screeningMedicineRadiologyComputer visionPathologyLung Cancer Diagnosis and TreatmentRadiomics and Machine Learning in Medical ImagingAdvanced X-ray and CT Imaging
A robust deep learning algorithm for lung cancer detection from computed tomography images | Litcius