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Discovery of urea-based pleuromutilin derivatives as potent gram-positive antibacterial agents

Zhenhua Wu, Xiaoli Zhu, Anjin Hong, Guanghui He, Zheng Wang, Qingyan Xu, Zhiyu Hu, Xiaobing Wu, Yuezhou Wang, Qiufang Chen, Xilin Zhao, Li Li, Xianming Deng

2023Bioorganic Chemistry12 citationsDOI

Topics & Concepts

ChemistryStaphylococcus aureusAntibacterial activityAntibioticsMicrobiologyAntimicrobialThioureaIn vivoAntibiotic resistanceBacteriaMinimum inhibitory concentrationUreaCombinatorial chemistryBiochemistryBiologyOrganic chemistryBiotechnologyGeneticsVeterinary medicine and infectious diseasesPharmacological Effects of Natural CompoundsToxin Mechanisms and Immunotoxins
Discovery of urea-based pleuromutilin derivatives as potent gram-positive antibacterial agents | Litcius