Synthesis of two novel pyrazolo[1,5-a]pyrimidine compounds with antibacterial activity and biophysical insights into their interactions with plasma protein
Ling‐Ling He, Qi Qi, Xin Wang, Xin Wang, Yuli Li, Yao Zhu, Xiaofang Wang, Xiaofang Wang, Liang Xu
Topics & Concepts
ChemistryHydrogen bondCircular dichroismBovine serum albuminPyrimidineQuenching (fluorescence)FluorescenceFluorescence spectroscopyHydrophobic effectStereochemistryOrganic chemistryMoleculeChromatographyQuantum mechanicsPhysicsProtein Interaction Studies and Fluorescence AnalysisDrug Transport and Resistance MechanismsMetal complexes synthesis and properties