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A scalable approach to characterize pleiotropy across thousands of human diseases and complex traits using GWAS summary statistics

Zixuan Zhang, Junghyun Jung, Artem Kim, Noah Suboc, Steven Gazal, Nicholas Mancuso

2023The American Journal of Human Genetics18 citationsDOIOpen Access PDF

Topics & Concepts

PleiotropyBiobankGenome-wide association studyComputational biologyBiologyGenetic associationPhenotypeComputer scienceGeneticsSingle-nucleotide polymorphismGenotypeGeneGenetic Associations and EpidemiologyGenetic and phenotypic traits in livestockEpigenetics and DNA Methylation
A scalable approach to characterize pleiotropy across thousands of human diseases and complex traits using GWAS summary statistics | Litcius