EdU Incorporation To Assess Cell Proliferation and Drug Susceptibility in Naegleria fowleri
Emma V. Troth, Dennis E. Kyle
Abstract
. EdA (7-deaza-2'-deoxy-7-ethynyladenosine), an adenine analog, also was incorporated by N. fowleri but was more cytotoxic than EdU. In summary, EdU incorporation could be used as a complimentary method for drug discovery for these neglected pathogens.
Topics & Concepts
Naegleria fowleriBiologyDrug discoveryCell growthDrugChemistryPharmacologyVirologyBiochemistryMeningoencephalitisLegionella and Acanthamoeba researchVibrio bacteria research studiesHeme Oxygenase-1 and Carbon Monoxide