Deliver anti-PD-L1 into brain by p-hydroxybenzoic acid to enhance immunotherapeutic effect for glioblastoma
Haiyan Guo, Ruifeng Wang, Dongli Wang, Songli Wang, Jianfen Zhou, Zhilan Chai, Shengyu Yao, Jinyang Li, Linwei Lu, Yu Liu, Cao Xie, Weiyue Lu
Topics & Concepts
ConjugateGlioblastomaAntibodyTranscytosisGliomaCancer researchBlockadeImmune systemImmune checkpointMonoclonal antibodyChemistryBlood–brain barrierLigand (biochemistry)Distribution (mathematics)ReceptorMedicinePharmacologyImmunologyCentral nervous systemBiochemistryInternal medicineMathematicsMathematical analysisEndocytosisGlioma Diagnosis and TreatmentCancer Immunotherapy and BiomarkersCAR-T cell therapy research