Litcius/Paper detail

Therapeutic base editing of human hematopoietic stem cells

Jing Zeng, Yuxuan Wu, Chunyan Ren, Jasmine Bonanno, Anne H. Shen, Devlin Shea, Jason M. Gehrke, Kendell Clement, Kevin Luk, Qiuming Yao, Rachel Kim, Scot A. Wolfe, John Manis, Luca Pinello, J. Keith Joung, Daniel E. Bauer

2020Nature Medicine280 citationsDOIOpen Access PDF

Topics & Concepts

HaematopoiesisStem cellRibonucleoproteinCD34BiologyGenome editingNucleotideCell biologyComputational biologyGeneticsCRISPRRNAGeneCRISPR and Genetic EngineeringCytomegalovirus and herpesvirus researchVirus-based gene therapy research