IFNγ-induced PD-L1 expression in ovarian cancer cells is regulated by JAK1, STAT1 and IRF1 signaling
Sveta Padmanabhan, Bijaya Gaire, Yue Zou, Mohammad M. Uddin, Ivana Vancurova
Topics & Concepts
IRF1STAT1Cancer researchBiologyChromatin immunoprecipitationCell biologyTranscription factorInterferonIRF8PD-L1Signal transductionChemistryImmune systemGene expressionPromoterImmunologyGeneImmunotherapyBiochemistryCytokine Signaling Pathways and InteractionsImmune Cell Function and InteractionCancer-related molecular mechanisms research