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Tail approach synthesis of novel benzenesulfonamides incorporating 1,3,4-oxadiazole hybrids as potent inhibitor of carbonic anhydrase I, II, IX, and XII isoenzymes

Vikas Sharma, Rajiv Kumar, Andrea Angeli, Claudiu T. Supuran, Pawan K. Sharma

2020European Journal of Medicinal Chemistry35 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryCarbonic anhydraseOxadiazoleIsozymeCarbonic anhydrase inhibitorBiochemistrySulfonamideEnzyme inhibitorEnzymeStereochemistryOrganic chemistryEnzyme function and inhibitionSynthesis and Catalytic ReactionsChemical Reactions and Mechanisms
Tail approach synthesis of novel benzenesulfonamides incorporating 1,3,4-oxadiazole hybrids as potent inhibitor of carbonic anhydrase I, II, IX, and XII isoenzymes | Litcius