Inhibition of ABCG2 transporter by lapatinib enhances 5-aminolevulinic acid-mediated protoporphyrin IX fluorescence and photodynamic therapy response in human glioma cell lines
Matthew Mansi, Richard Howley, Sharayu Chandratre, Bin Chen
Topics & Concepts
Protoporphyrin IXPhotodynamic therapyFerrochelataseAbcg2ChemistryGliomaIntracellularCancer researchPharmacologyCell cultureExtracellularLapatinibBiochemistryEffluxHemeTransporterATP-binding cassette transporterBiologyCancerEnzymeTrastuzumabGeneOrganic chemistryGeneticsBreast cancerDrug Transport and Resistance MechanismsNanoplatforms for cancer theranosticsPhotodynamic Therapy Research Studies