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Computational identification of a systemic antibiotic for Gram-negative bacteria

Ryan D. Miller, Akira Iinishi, Seyed Majed Modaresi, Byung‐Kuk Yoo, Thomas D. Curtis, Patrick J. Lariviere, Libang Liang, Sangkeun Son, Samantha Nicolau, Rachel Bargabos, Madeleine Morrissette, Michael F. Gates, Norman Pitt, Roman P. Jakob, Parthasarathi Rath, Timm Maier, Andrey Malyutin, Jens T. Kaiser, Samantha Niles, Blake Karavas, Meghan Ghiglieri, Sarah Bowman, Douglas C. Rees, Sebastian Hiller, Kim Lewis

2022Nature Microbiology137 citationsDOIOpen Access PDF

Topics & Concepts

BamaBiologyOperonAntibioticsPhotorhabdusComputational biologyMicrobiologyDrug discoveryGram-negative bacteriaEscherichia coliGeneBacterial outer membraneGeneticsBioinformaticsInsect symbiosis and bacterial influencesGenomics and Phylogenetic StudiesMicrobial Natural Products and Biosynthesis
Computational identification of a systemic antibiotic for Gram-negative bacteria | Litcius