Presymptomatic Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 Among Residents and Staff at a Skilled Nursing Facility: Results of Real-time Polymerase Chain Reaction and Serologic Testing
Scott A. Goldberg, Jochen K. Lennerz, Michael Klompas, Eden Mark, Virginia Pierce, Ryan W. Thompson, Charles T. Pu, Lauren L. Ritterhouse, Anand S. Dighe, Eric Rosenberg, David C. Grabowski
Abstract
High rates of asymptomatic coronavirus disease 2019 infection suggest benefits to routine testing in congregate care settings. Screening was undertaken in a single nursing facility without a known case of coronavirus disease 2019, demonstrating an 85% prevalence among residents and 37% among staff. Serology was not helpful in identifying infections.
Topics & Concepts
AsymptomaticMedicineSerologySkilled Nursing FacilityTransmission (telecommunications)CoronavirusCoronavirus disease 2019 (COVID-19)DiseaseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Polymerase chain reactionVirologyIntensive care medicineNursingEmergency medicineImmunologyInternal medicineAntibodyInfectious disease (medical specialty)GeneBiologyEngineeringElectrical engineeringBiochemistrySARS-CoV-2 detection and testingCOVID-19 Clinical Research StudiesCOVID-19 and healthcare impacts