Transcranial ultrasound localization microscopy in moyamoya patients using a clinical ultrasound system
Louise Denis, Elena Meseguer, Augustin Gaudemer, Georges Jaklh, Sylvain Bodard, Georges Chabouh, Dominique Hervé, Éric Vicaut, Pierre Amarenco, Olivier Couture
Abstract
Using a low-frame-rate ultrasound scanner, CEUS and accessible post-processing tools, we demonstrate that transcranial ULM can facilitate the visualization and characterization of perforating arteries, even in cases where they were previously undetectable using standard non-invasive imaging techniques. We speculate that with the advent of high-frame-rate 3D ULM, this technique may find widespread utility in hospitals.
Topics & Concepts
UltrasoundTranscranial DopplerMoyamoya diseaseMicroscopyMedicineRadiologyBiomedical engineeringPathologyCerebrovascular and Carotid Artery DiseasesMoyamoya disease diagnosis and treatmentAortic Disease and Treatment Approaches