Azithromycin-Resistant <i>Salmonella enterica</i> Serovar Typhi AcrB-R717Q/L, Singapore
Sophie Octavia, Ka Lip Chew, Raymond Tzer Pin Lin, Jeanette Teo
Abstract
In Singapore, the incidence of typhoid fever is low (0.8-1.2 cases/100,000 population annually). Most cases are imported, particularly from the South Asia subcontinent (1). First-line treatments include ampicillin, trimethoprim/sulfamethoxazole, and chloramphenicol. With increasing multidrug-resistant and fluoroquinolone-resistant infections, ceftriaxone and azithromycin are the next treatment alternatives. However, resistance to ceftriaxone or azithromycin resistance has been reported (2).
Topics & Concepts
Salmonella typhiSalmonella entericaSerotypeSalmonellaAzithromycinMicrobiologyMultiple drug resistanceBiologyVirologyEnvironmental healthMedicineDrug resistanceBacteriaAntibioticsGeneGeneticsEscherichia coliBiochemistrySalmonella and Campylobacter epidemiologyAntibiotic Resistance in BacteriaVibrio bacteria research studies