Litcius/Paper detail

Computing cliques and cavities in networks

Dinghua Shi, Zhifeng Chen, X. H. Sun, Qinghua Chen, Chuang Ma, Yang Lou, Guanrong Chen

2021Communications Physics43 citationsDOIOpen Access PDF

Abstract

Abstract Complex networks contain complete subgraphs such as nodes, edges, triangles, etc., referred to as simplices and cliques of different orders. Notably, cavities consisting of higher-order cliques play an important role in brain functions. Since searching for maximum cliques is an NP-complete problem, we use k-core decomposition to determine the computability of a given network. For a computable network, we design a search method with an implementable algorithm for finding cliques of different orders, obtaining also the Euler characteristic number. Then, we compute the Betti numbers by using the ranks of boundary matrices of adjacent cliques. Furthermore, we design an optimized algorithm for finding cavities of different orders. Finally, we apply the algorithm to the neuronal network of C. elegans with data from one typical dataset, and find all of its cliques and some cavities of different orders, providing a basis for further mathematical analysis and computation of its structure and function.

Topics & Concepts

Euler's formulaComputer scienceComputabilityComputationBetti numberCliqueGeometric networksBoundary (topology)Theoretical computer scienceFunction (biology)CombinatoricsMathematicsAlgorithmDiscrete mathematicsComplex networkEvolutionary biologyBiologyMathematical analysisComputational Drug Discovery MethodsPhotoreceptor and optogenetics researchBioinformatics and Genomic Networks