Recent advancements in the therapeutic approaches for Alzheimer's disease treatment: current and future perspective
Amit Sharma, Santosh Rudrawar, Sandip B. Bharate, Hemant R. Jadhav
Abstract
Present-day research focuses on multi-target directed ligands (MTDLs), which inhibit multiple factors simultaneously, helping slow the disease's progression. This review attempts to collate the recent information related to proposed hypotheses for AD etiology. It systematically organizes the advances in various therapeutic options for AD, with a particular emphasis on clinical candidates. Also, it is expected to help medicinal chemists design novel AD treatments based on available information, which could be helpful to AD patients.
Topics & Concepts
Perspective (graphical)Current (fluid)DiseaseAlzheimer's diseaseMedicineIntensive care medicinePsychologyComputer scienceEngineeringInternal medicineArtificial intelligenceElectrical engineeringCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsComputational Drug Discovery Methods