Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches
Eman S. Tantawy, Atef M. Amer, Enaiat K. Mohamed, Mohamed M. Abd Alla, Mohamed S. Nafie
Topics & Concepts
ChemistryPyrazineIn silicoCombinatorial chemistryStereochemistryIn vitroMTT assayA549 cellIC50Docking (animal)CytotoxicityMolecular modelBiochemistryMedicineNursingGeneSynthesis and Biological EvaluationBioactive Compounds and Antitumor AgentsSynthesis and biological activity