Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations
Olivia C. Leavy, Shwu‐Fan Ma, Philip L. Molyneaux, Toby M. Maher, Justin M. Oldham, Carlos Flores, Imre Noth, Gísli Jenkins, Frank Dudbridge, Louise V. Wain, Richard J. Allen
Abstract
<p>Understanding how genetic factors contribute to disease risk improves our understanding of pathogenesis, supports drug development, and aids risk prediction (1). Appropriate quantification and interpretation of this contribution is essential for measuring the impact of genetic variation and in motivating and informing future studies. </p>
Topics & Concepts
MedicineIdiopathic pulmonary fibrosisPulmonary fibrosisFibrosisGeneticsInternal medicineLungBiologyInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis