Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring
Luodan Yang, Yan Dong, Chongyun Wu, Hannah Youngblood, Yong Li, Xuemei Zong, Lei Li, Tongda Xü, Quanguang Zhang
Abstract
Prenatal PBM treatment exerts neuroprotective effects on neonatal HI rats. Underlying mechanisms for this neuroprotection may include preservation of mitochondrial function, reduction of inflammation, and decreased oxidative stress. Our findings support the possible use of PBM treatment in high-risk pregnancies to alleviate or prevent HI-induced brain injury in the perinatal period.
Topics & Concepts
MedicineNeuroprotectionOxidative stressHippocampusNeuroinflammationAnesthesiaBrain damageIschemiaInternal medicineInflammationLaser Applications in Dentistry and MedicineHydrogen's biological and therapeutic effectsConnexins and lens biology