Anticancer Biological Profile of Some Heterocylic Moieties-Thiadiazole, Benzimidazole, Quinazoline, and Pyrimidine
Parin Salim Sidat, Tasneem Mohamadbin Kasim Jaber, Shwetang Ramesh Vekariya, Azmin Mahervan Mogal, Aarifa Mustak Patel, Malleshappa N. Noolvi
Abstract
Several five and six-membered aromatic systems with three heteroatoms such as S, O, and N have been intensively researched due to their intriguing pharmacological properties. Heterocyclic compounds are chemicals that allow life to exist. Aside from that, all heteroatoms in the ring interact better with amino acids, and these interactions aid in reducing transactivation, and enhancing lipophilicity, solubility, and absorption, all of which can be exploited to improve therapeutic action. Heterocyc
Topics & Concepts
HeteroatomLipophilicityBenzimidazolePyrimidineChemistryQuinazolineTransactivationRing (chemistry)Combinatorial chemistryBiological activityOrganic chemistryStereochemistryBiochemistryIn vitroTranscription factorGeneSynthesis and biological activityQuinazolinone synthesis and applicationsSynthesis and Characterization of Heterocyclic Compounds