PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape
Noah Gamble, Alexandra Bradu, Jason A. Caldwell, Joshua A. McKeever, Olubusayo Bolonduro, Ebru Ermis, Caroline Kaiser, YeEun Kim, Benjamin Parks, Sandy Klemm, William J. Greenleaf, Gerald R. Crabtree, Andrew S. Koh
Topics & Concepts
EffectorRUNX1ChromatinBiologyCell biologyTranscription factorChromatin remodelingPriming (agriculture)SWI/SNFGeneticsStem cellHaematopoiesisGeneBotanyGerminationT-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune Responses