Litcius/Paper detail

Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities

Cheng Zhang, Yue Hu, Ping Sun, Lei Hua, Shuli Liang, Yitao Ou, Dan Wu, Xinyi Wu, Hao Chen, Ying Hao, Wenhui Hu, Zhongjin Yang

2021European Journal of Medicinal Chemistry29 citationsDOIOpen Access PDF

Topics & Concepts

InflammasomeChemistryChalconeInflammationPharmacologyLead compoundBiochemistryIn vitroStereochemistryReceptorImmunologyBiologyInflammasome and immune disordersMacrophage Migration Inhibitory FactorCholesterol and Lipid Metabolism