Litcius/Paper detail

Tree House Explorer: A Novel Genome Browser for Phylogenomics

Andrew J. Harris, Nicole M. Foley, Tiffani L. Williams, William J. Murphy

2022Molecular Biology and Evolution10 citationsDOIOpen Access PDF

Abstract

Tree House Explorer (THEx) is a genome browser that integrates phylogenomic data and genomic annotations into a single interactive platform for combined analysis. THEx allows users to visualize genome-wide variation in evolutionary histories and genetic divergence on a chromosome-by-chromosome basis, with continuous sliding window comparisons to gene annotations (GFF/GTF), recombination rates, and other user-specified, highly customizable feature annotations. THEx provides a new platform for interactive phylogenomic data visualization to analyze and interpret the diverse evolutionary histories woven throughout genomes. Hosted on Conda, THEx integrates seamlessly into new or pre-existing workflows.

Topics & Concepts

PhylogenomicsBiologyGenomeVisualizationTree (set theory)Genome browserWorkflowChromosomePhylogenetic treeGenomicsComputational biologyEvolutionary biologyGeneComputer scienceGeneticsData miningCladeDatabaseMathematical analysisMathematicsGenomics and Phylogenetic StudiesGenetic diversity and population structureEvolution and Genetic Dynamics
Tree House Explorer: A Novel Genome Browser for Phylogenomics | Litcius