Ruxolitinib can cause weight gain by blocking leptin signaling in the brain via JAK2/STAT3
Nicole Mollé, Spencer Krichevsky, Pouneh Kermani, Richard T. Silver, Ellen K. Ritchie, Joseph M. Scandura
Topics & Concepts
RuxolitinibBlocking (statistics)LeptinSignal transductionMedicineInternal medicinePharmacologyBiologyMyelofibrosisObesityCell biologyComputer scienceComputer networkBone marrowMyeloproliferative Neoplasms: Diagnosis and TreatmentCytokine Signaling Pathways and InteractionsKruppel-like factors research