Genome-Wide CRISPR Screen Identifies Semaphorin 6A and 6B as Receptors for Paeniclostridium sordellii Toxin TcsL
Songhai Tian, Yang Liu, Hao Wu, Hao Liu, Ji Zeng, Mei Yuk Choi, Hong Chen, Ralf Gerhard, Min Dong
Topics & Concepts
BiologyReceptorExotoxinSemaphorinFrizzledClostridium difficile toxin BToxinCell cultureVirulence factorVirulenceMolecular biologyClostridium difficile toxin ACell biologyMicrobiologyGeneticsWnt signaling pathwayGeneSignal transductionClostridium difficileAntibioticsClostridium difficile and Clostridium perfringens researchToxin Mechanisms and ImmunotoxinsPharmacological Effects of Natural Compounds