The intricate interplay between HIFs, ROS, and the ubiquitin system in the tumor hypoxic microenvironment
Yijie Wang, Xiong Liu, Weixiao Huang, Junjie Liang, Yan Chen
Topics & Concepts
Ubiquitin ligaseUbiquitinCarcinogenesisBiologyCell biologyTumor microenvironmentDownregulation and upregulationHypoxia-inducible factorsSignal transductionCancer researchTumor progressionPost-translational regulationCancerBiochemistryPhosphorylationGeneticsTumor cellsGeneUbiquitin and proteasome pathwaysCancer, Hypoxia, and MetabolismHistone Deacetylase Inhibitors Research