A Glucose Sensor Based on Surface Functionalized MXene
Yixuan Huang, Ziyang Long, Jihua Zou, Lingzhi Luo, Xiangyu Zhou, Hezhuang Liu, Weijie He, Kai Shen, Jiang Wu
Abstract
Biosensor based on surface functionalized MXene for sensitive enzymatic glucose detection is reported. We intentionally generate a few defects and increase surface hydroxyl groups on the surface of MXene-Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> as binding sites for the bioreceptor immobilization. The biosensor utilizes the excellent electrical conductivity and abundant active sites of functionalized MXene, providing a transfer channel for the electrons generated by the redox reaction between glucose oxidase (GOx) enzyme and glucose. The sensor exhibits a high sensitivity up to 5.1 A/A for 10 mM glucose. Furthermore, we developed a glucose data collection and sharing system based on a cloud platform, ensuring the sensor detection error controlled within 10%. Therefore, the surface functionalized MXene reported in this work is emerged as a potential candidate for electrochemical biosensors.