Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Neeraj Kumar, Damini Sood, Ramesh Chandra
Abstract
immunization assay showed the reliable elicitation of key players in terms of immune cells together with memory cells to evoke adaptive immune responses upon administration of the construct. In view of favorable outcomes, we also propose a plausible vaccine mechanism to elicit an immune response to fight coronavirus.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)VirologyProtein subunit2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineComputational biologyBiologyInternal medicineGeneticsOutbreakGeneInfectious disease (medical specialty)Diseasevaccines and immunoinformatics approachesSARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery Methods