The long and winding road of designing phosphodiesterase inhibitors for the treatment of heart failure
Nathália Fonseca Nadur, Luciana Luiz de Azevedo, Lucas Caruso, Cedric Stephan Graebin, Renata Barbosa Lacerda, Arthur Eugen Kümmerle
Topics & Concepts
ChemistryPhosphodiesteraseHeart failurecGMP-specific phosphodiesterase type 5Enzyme inhibitorPharmacologyEnzymeInternal medicineBiochemistrySildenafilMedicinePhosphodiesterase function and regulationHeart Failure Treatment and ManagementCholinesterase and Neurodegenerative Diseases