Discovery of pyran annulated heterocyclic scaffolds linked to carboxamide fragments: Anticancer evaluation, topoisomerase I/II, tyrosine kinase receptor inhibition and molecular docking studies
Ahmed M. Fouda, Raafat A. El‐Eisawy, Mohammed A. A. El-Nassag, Hany M. Mohamed, Ashraf H.F. Fekry, Heba K. Abd El-Mawgoud, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Ahmed A. Elhenawy, Ahmed Mora, Ahmed M. El‐Agrody
Topics & Concepts
ChemistryTopoisomeraseDocking (animal)Cell cultureIn vitroReceptor tyrosine kinaseTyrosine kinaseKinaseEnzymeStereochemistryBiochemistryPharmacologyReceptorNursingBiologyGeneticsMedicineSynthesis and biological activityCancer therapeutics and mechanismsBioactive Compounds and Antitumor Agents