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An Outbreak of COVID-19 among mRNA-Vaccinated Nursing Home Residents

Fabrizio Faggiano, Maicol Andrea Rossi, Tiziana Cena, Fulvia Milano, Antonella Barale, Quenya Ristagno, Virginia Silano

2021Vaccines14 citationsDOIOpen Access PDF

Abstract

An outbreak was described among the guests of a Long-Term Care Facility in the North of Italy. Among 23 guests, 20 of whom were fully vaccinated with BNT162b2 vaccine, the outbreak led to a final count of 11 positive guests, 9 of whom were vaccinated, and 4 positive healthcare workers, of whom only 1 was vaccinated. Eight of the positive guests (six vaccinated and two unvaccinated) had symptoms that in five cases (three vaccinated and two unvaccinated) led to death. The risk of infection and the risk of death appeared not to be correlated with the health status neither with the serological titer, but only with age.

Topics & Concepts

OutbreakMedicineCoronavirus disease 2019 (COVID-19)TiterVaccinationSerologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Nursing homes2019-20 coronavirus outbreakHealth careVirologyEnvironmental healthFamily medicineImmunologyNursingInternal medicineDiseaseAntibodyVirusInfectious disease (medical specialty)EconomicsEconomic growthSARS-CoV-2 and COVID-19 ResearchVaccine Coverage and HesitancyViral gastroenteritis research and epidemiology
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